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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Mycophenolic Acid and NAD

supplement:

NAD

Research Papers that Mention the Interaction

Mycophenolic acid … NAD+ , with a intercept inhibition constant (Kii) of 0.03 ± 0.004 μM. Tiazofurin and its seleno analog were not inhibitory to the purified … nonhydrolyzable β-methylene derivatives of TAD or SAD were inhibitory, with Kii values 13- to 60-fold higher than that of mycophenolic acid.
Antimicrobial Agents and Chemotherapy  •  2005  |  View Paper
Extracts of these E. coli cells contained IMPDH activity that had an apparent … IMP of 21.7 +/- 0.3 microM and an apparent Km for NAD of 314 +/- 84 microM (mean +/- standard error of …; n = 3), and the activity was inhibited by mycophenolic acid (50% inhibitory concentration, …; n = 2).
Antimicrobial agents and chemotherapy  •  1997  |  View Paper