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“Therefore, we investigated whether the modulatory effect of taurine on γ‐aminobutyric acid (GABA)A receptors can enhance the anticonvulsive potential of the GABAA receptor agonist muscimol and of the barbiturate pentobarbital.”
Pharmacology Biochemistry and Behavior • 1993 | View Paper
“The phenylsuccinylimido derivatives of taurine appeared to increase the binding of muscimol in micromolar concentrations, while taurine decreased it slightly.”
“Release of taurine , not hitherto considered a neurotransmitter in this brain area, is depressed by muscimol (10 microM) and pentobarbitone and increased by picrotoxin (15 microM).”