Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Morphine and Serine

supplement:

Serine

Research Papers that Mention the Interaction

Morphine decreased the NMDA receptor‐mediated excitatory postsynaptic currents and excitability of GABAergic neurons in the NAc, while exogenous d‐serine alleviated the effects of morphine.
Addiction biology  •  2017  |  View Paper
While the intracerebroventricular (icv) administration of morphine to mice rapidly reduced the association of MORs with G proteins, it increased the serine phosphorylation of these receptors.
Neuropharmacology  •  2008  |  View Paper
In addition, we showed that the ability of morphine withdrawal to stimulate phosphorylation at serine 31 is reduced (101.7 ± 7.7%, P < 0.05) by SL327 (100 mg/kg, i.p.),
Basic Research in Cardiology  •  2008  |  View Paper
Morphine caused serine phosphorylation of the IR and impaired the formation of the signaling complex among the IR, Shc, and Grb2.
Molecular and Cellular Biology  •  2003  |  View Paper