supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Morphine
supplement:
Masoprocol
Research Papers that Mention the Interaction
“… NDGA (10, 20 μg), a nonselective LOX inhibitor, AA‐861 (1.….8 μg), a 12‐LOX selective inhibitor, concurrently with systemic morphine for 5 days or as a single injection immediately preceding naloxone challenge, blocked the … immunoreactive neurons in the dorsal horn, and significantly attenuated the morphine withdrawal syndrome.”
Spinal administration of lipoxygenase inhibitors suppresses behavioural and neurochemical manifestations of naloxone‐precipitated opioid withdrawal“Also, nordihydroguaiaretic acid (5-lipooxygenase inhibitor) was able to block the naloxone-induced contracture following exposure to morphine when injected before or after the opioid agonist.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback