Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Morphine and Isothiocyanate

supplement:

Isothiocyanate

Research Papers that Mention the Interaction

Both BFNA (68%) and Ntii (100%) in the PAG significantly reduced morphine , but not beta-endorphin analgesia in the amygdala on the tail-flick test.
Brain Research  •  1996  |  View Paper
Pretreatment of mice with the delta-2 antagonist, 5'-isothiocyanate , also did not antagonize the antinociceptive effects of morphine but blocked the leftward displacement in the morphine dose-response curve associated with CWSS, suggesting involvement of an opioid delta-2 receptor in this effect.
The Journal of pharmacology and experimental therapeutics  •  1993  |  View Paper