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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Morphine and Glutamate

supplement:

Glutamate

Research Papers that Mention the Interaction

Morphine depressed the excitatory action of L-glutamate and of acetylcholine by a naloxone-antagonisable mechanism.
Brain Research  •  1976  |  View Paper
Morphine excited cholinoceptive neurones and enhanced the excitatory actins of acetylcholine and L-glutamate.
Brain Research  •  1976  |  View Paper
Amnesia induced by pretraining morphine was significantly reversed by pretest administration of L-glutamate (0.0001 and 0.001 μg/mouse, i.c.v.).
The International journal of neuroscience  •  2006  |  View Paper
The opiate agonists morphine and D-Met2-Pro5-enkephalinamide by themselves did not influence the spontaneous release of [3H]AD from the cortex but both agents very effectively inhibited the release evoked by L-Glu.
Canadian journal of physiology and pharmacology  •  1980  |  View Paper
Morphine , levorphanol and methionine-enkephalin depressed the spontaneous discharge of respiration related units and the firing induced in these cells by phoretically applied L-glutamate.
Brain Research  •  1978  |  View Paper
Abstract Microelectrophoretically applied morphine depressed spontaneously discharging cortical neurones of rats and blocked excitation induced by electrophoretic administrations of either acetylcholine or l-glutamate.
Life sciences  •  1975  |  View Paper