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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Mitoxantrone
supplement:
Vitamin K
Research Papers that Mention the Interaction
“ Vitamin K3 and plumbagin specifically inhibited the ABCG2-mediated efflux of mitoxantrone but did not have any effect on the ABCB1-mediated efflux of rhodamine 123.”
The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance–linked ATP binding cassette drug transporter ABCG2
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