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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Mitomycin and Tretinoin



Research Papers that Mention the Interaction

A synergism was found for ATRA and mitomycin or imatinib in CRMM-2, in contrast to CRMM-1, where antagonism was obtained.
British Journal of Ophthalmology  •  2012  |  View Paper
The combination of ATRA and 5-FU or MMC promoted cell apoptosis, and the mechanism involved in apoptosis may be related to inhibition of survivin gene expression.
Viability of the cells decreased significantly after combined treatment with ATRA and 5-fluorouracil (5-FU) or mitomycin c (MMC) and was evaluated by fluorescence microscopy.
Chinese medical journal  •  2008  |  View Paper
Conclusion: Intraoperative single-dose administration of RA and MMC significantly prevented the development of PCO in rabbit eyes.
Graefe's Archive for Clinical and Experimental Ophthalmology  •  2001  |  View Paper
The growth of the cells was inhibited by 37% and 93%, respectively, by the 3-day treatment with Ro 10-9359 and Ro 10-1670, at the concentration of 5 X 10(-5) M. The retinoids given in combination with MMC produced additive effects.
Hinyokika kiyo. Acta urologica Japonica  •  1984  |  View Paper