Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Mitomycin and Flavone Acetic Acid

Research Papers that Mention the Interaction

After FAA transduction of mutant progenitor cells, either colony number or colony size increased in the presence of MMC.
Blood  •  1997  |  View Paper
We have reported enhancement of the combined antitumor effects of MMC plus FAA and hyperthermia (HT).
Anti-cancer drugs  •  1997  |  View Paper
Antitumor response obtained in animals treated with FAA plus MMC with HT was clearly better than that obtained in any of the other groups.
In the present study, we investigated whether FAA could increase the cytotoxicity of mitomycin C (MMC), a bioreductive drug with selective cytotoxicity against hypoxic cells, under either normothermic or hyperthermic conditions.
Cancer Chemotherapy and Pharmacology  •  1996  |  View Paper
We used B 16 melanoma cells both in vitro and in vivo to determine whether Flavone acetic acid (FAA) can increase the cytotoxicity of mitomycin C (MMC) under normothermic and hyperthermic (HT) conditions.
Gan to kagaku ryoho. Cancer & chemotherapy  •  1993  |  View Paper
Since the microenvironmental consequences of induced ischaemia are reductions in both oxygenation and pH these parameters are probably responsible in large part for the enhancement of cytotoxicity observed when MMC and FAA are combined.
Anticancer research  •  1993  |  View Paper