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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Mitomycin and Epinephrine



Research Papers that Mention the Interaction

Precis: The use of mitomycin-C as a mixed formulation with lidocaine and epinephrine for filtration surgery may alter its pH and consequently affect clinical effectivity.
Journal of glaucoma  •  2019  |  View Paper
When beta-adrenergic stimulants such as isoproterenol, epinephrine , terbutaline and turobuterol were added at concentrations over 10(-14) M 15 to 60 min before mitomycin C, the colony-forming ability of HeLa cells was significantly inhibited more than by mitomycin C alone.
Japanese journal of pharmacology  •  1982  |  View Paper
Among several sympathomimetic drugs, isoproterenol, epinephrine and norepinephrine significantly potentiated the cytotoxic effect and the uptake of MMC into rat ascites hepatoma AH130 cells in in vitro experiments, but salbutamol, tulobuterol and phenylephrine did not.
Japanese journal of pharmacology  •  1986  |  View Paper