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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Mitomycin and Cannabinoids

supplement:

Cannabinoids

Research Papers that Mention the Interaction

These major cannabinoids inhibited the 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin ( AMMC ) and dextromethorphan O-demethylase activities of recombinant CYP2D6 and pooled human liver microsomes in a concentration-dependent manner (IC50 = 4.01–24.9 μM), indicating the strongest inhibitory potency of CBD.
Drug Metabolism and Disposition  •  2011  |  View Paper