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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Mitomycin
supplement:
Astaxanthin
Research Papers that Mention the Interaction
“Combination of MMC and astaxanthin synergistically resulted in cytotoxicity and cell growth inhibition in NSCLC cells, accompanied with reduced phospho-AKT(Ser473) level and Rad51 expression.”
“These findings may provide rationale to combine astaxanthin with MMC for the treatment of NSCLC.”
Astaxanthin down-regulates Rad51 expression via inactivation of AKT kinase to enhance mitomycin C-induced cytotoxicity in human non-small cell lung cancer cells.
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