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Last Updated: 3 years ago

Possible Interaction: Minoxidil and Quercetin

drug:

Minoxidil

supplement:

Quercetin

Research Papers that Mention the Interaction

“ Quercetin inhibited the sulfation of dopamine, (-)-salbutamol, minoxidil and paracetamol and the IC50 values were 1 - 2 orders of magnitude greater in human duodenum than in the liver.”
Inhibition of human liver and duodenum sulfotransferases by drugs and dietary chemicals: a review of the literature.
International journal of clinical pharmacology and therapeutics  •  2004  |  View Paper
“ Quercetin inhibited the sulphation of 4-nitrophenol, dopamine, (-)-salbutamol, minoxidil and paracetamol both in liver and duodenum.”
Differential inhibition of human liver and duodenum sulphotransferase activities by quercetin, a flavonoid present in vegetables, fruit and wine
Xenobiotica; the fate of foreign compounds in biological systems  •  2001  |  View Paper
“… quercetin … minoxidil by human liver cytosol, partially purified P-form phenolsulfotransferase (PST), and recombinant P-form PST, with IC50 values of 0.025-0.095 microM. …-mediated sulfation, with IC50 values < 1 microM. Studies of structural analogs indicated the flavonoid 7-hydroxyl group as particularly important for potent inhibition.”
Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention.
Drug metabolism and disposition: the biological fate of chemicals  •  1996  |  View Paper