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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Minocycline
supplement:
3-Nitrotyrosine
Research Papers that Mention the Interaction
“ Minocycline pretreatment improved hair cell survival and significantly reduced the expression of iNOS and 3-NT in cochlear tissues compared with the streptomycin treatment group.”
Minocycline attenuates streptomycin-induced cochlear hair cell death by inhibiting protein nitration and poly (ADP-ribose) polymerase activation“…,minocycline administration suppressed inducible nitric … (iNOS) expression and nitrotyrosine production, inhibited proinflammatory cytokine expression, repressed the elevated mRNA expression of matrix metalloproteinases (MMPs) 2, 3, 9, and 13, diminished … apoptotic index in colonic tissues, and inhibited nitric oxide production in the serum of mice with DSS-induced acute colitis.”
“Administration of the broad spectrum anti-inflammatory agent minocycline or the selective iNOS inhibitor 1400W markedly reduced 3-NT levels.”
“ Minocycline treatment strongly diminished the extent of 3-nitrotyrosine immunoreactivity.”
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