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Last Updated: 3 months ago

Possible Interaction: Mifepristone and Progesterone

supplement:

Progesterone

Research Papers that Mention the Interaction

high dose progesterone could inhibit the growth, promote apoptosis and inhibit … could inhibit the growth and promote apoptosis, MIF + MPA could more strongly inhibit the growth, promote apoptosis and inhibit metastasis of endometrial carcinoma … synergistic effect was observed on the expression of PCNA, ER, PR, bax and bcl-2.
Zhonghua fu chan ke za zhi  •  2003  |  View Paper
CONCLUSION(S) The effect of mifepristone on endometrial steroid receptors was consistent with functional inhibition of progesterone.
The effect of mifepristone on endometrial steroid receptors was consistent with functional inhibition of progesterone.
Fertility and sterility  •  2002  |  View Paper
CONCLUSIONS Our study showed an anti-proliferative effect on ovarian BRCA1-/2- MSC on in vitro combined treatment with mifepristone and progesterone.
CONCLUSIONS Our study showed an anti-proliferative effect on ovarian BRCA1-/2- MSC on in vitro combined treatment with mifepristone and progesterone.
Acta obstetricia et gynecologica Scandinavica  •  2019  |  View Paper
The synthesis of mifepristone , an antiprogestin blocking the action of progesterone at the receptor level, started a new era of medical termination of pregnancy (MTOP).
BJOG : an international journal of obstetrics and gynaecology  •  2017  |  View Paper
Progesterone use to reverse the effects of mifepristone.
This study demonstrated that mifepristone blockage of progesterone receptors was reversible, and that progesterone rescue could block the abortifacient effect of mifepristone if given soon after mifepristone dosing.
Issues in law & medicine  •  2017  |  View Paper
One published case series detailed a potential method to counter/reverse the abortifacient effect of mifepristone by administering parenteral progesterone in such situations.
Progesterone use in early pregnancy is low risk and its application to counter the effects of mifepristone in such circumstances may be clinically beneficial in preserving her threatened pregnancy.
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception  •  2017  |  View Paper
Mifepristone (RU486) blocked the immunosuppressive effect of progesterone.
Reproductive Biology and Endocrinology  •  2015  |  View Paper
CONCLUSION Mifepristone can inhibit the effects of progesterone by down-regulating the expressions of HLA-G, HLA-E and HLA-F mRNA in trophoblasts during the first trimester.
CONCLUSION Mifepristone can inhibit the effects of progesterone by down-regulating the expressions of HLA-G, HLA-E and HLA-F mRNA in trophoblasts during the first trimester.
Zhonghua yi xue za zhi  •  2012  |  View Paper
The agonistic effect of progesterone on SULT1E1 mRNA was concentration-dependently antagonized by RU486 ( mifepristone ) and ZK137316 and, with lower potency, by 4-nonylphenol, bisphenol A and apigenin.
Toxicology and applied pharmacology  •  2012  |  View Paper
Progesterone competes with mifepristone for the progesterone receptor and may reverse the effects of mifepristone.
The Annals of pharmacotherapy  •  2012  |  View Paper
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