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Last Updated: 24 days ago

Possible Interaction: Mibefradil and Calcium Supplement

Research Papers that Mention the Interaction

They also observed that mibefradil reduced the surface expression of β2 integrins and L-selectin and inhibited the fMLP induced calcium rise, indicating that mibefradil interferes with the integrin signaling through blocking the intracellular Ca2+ rise.
Cardiovascular Drugs and Therapy  •  2004  |  View Paper
The Ca2+ signals evoked by alkaline pH and progesterone are inhibited by the Cav channel blockers NNC 55-0396 and mibefradil.
Nature  •  2011  |  View Paper
Mibefradil was able to significantly inhibit the formyl-methionyl-leucyl-phenylalanine (fMLP) induced calcium rise, which suggests that mibefradil interfered with integrin signaling through blocking the intracellular calcium rise.
Cardiovascular Drugs and Therapy  •  2004  |  View Paper
Mibefradil inhibited Ca2+‐activated Cl− currents, ICl, Ca , activated by loading CPAE cells via the patch pipette with 500 nM free Ca2+ (Ki=4.7±0.18 μM, n=8).
British journal of pharmacology  •  1997  |  View Paper
Mibefradil is a new calcium antagonist that can inhibit cardiac calcium current without reducing myocardial force development.
The Journal of pharmacology and experimental therapeutics  •  1996  |  View Paper
A panel of various OR ligands induced Ca2+ signals in human spermatozoa, which could be inhibited by mibefradil.
Front. Mol. Biosci.  •  2016  |  View Paper