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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Mexiletine
supplement:
Phenylalanine
Research Papers that Mention the Interaction
“High-affinity binding of mexiletine in the open states of Nav1.4 and Nav1.5 was caused by a π–π interaction with Phe , whereas mexiletine was located away from Phe in the open state of Nav1.2.”
Mexiletine Block of Voltage-Gated Sodium Channels: Isoform- and State-Dependent Drug–Pore Interactions
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