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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Metronidazole
supplement:
Vitamin C
Research Papers that Mention the Interaction
“8HQ, VitC , CAT and SOD induced dose-related protective responses against DNA damage due to MZ and DZ.”
Evaluation of the genotoxic activity of metronidazole and dimetridazole in human lymphocytes by the comet assay.“Further, we evaluated the efficacy of vitamin C to reduce MTZ induced genotoxicity.”
“Further, vitamin C pre-treatment also reduced the genotoxicity indices following the combined treatment of MTZ and radiation.”
“Supplementation with vitamin C prior to MTZ treatment significantly reduced the frequency of CA (P<0.001) as well as MN (P<0.001).”
Effects of radiation and vitamin C treatment on metronidazole genotoxicity in mice.“The aqueous solubility of metronidazole can also be enhanced by solubilizing with a water-soluble vitamin, e.g., nicotinamide, ascorbic acid or pyridoxine HCl.”
Solubilization of metronidazole by water-miscible multi-cosolvents and water-soluble vitamins.
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