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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Metoprolol
supplement:
Xanthan Gum
Research Papers that Mention the Interaction
“Increasing XG concentrations provided faster MPT release rates characterised by zero-order release kinetics, no burst release was observed.”
Sustained-release and swelling characteristics of xanthan gum/ethylcellulose-based injection moulded matrix tablets: in vitro and in vivo evaluation.“While, in the gum formulations, the highest mean dissolution time and the lowest DE8% belonged to tablets with 100% xanthan, increasing the xanthan decreased the release rate of metoprolol , and formulations containing 80 and 100% xanthan had the USP dissolution standards.”
Use of Natural Gums and Cellulose Derivatives in Production of Sustained Release Metoprolol Tablets
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