supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Metoprolol
supplement:
Naringenin
Research Papers that Mention the Interaction
“Compared to the metoprolol control group, the C max, AUC, and half-life (T 1/2) of metoprolol increased in rats pre-treated with naringenin , while there was no significant change in T max.”
“The present study results revealed that naringenin significantly enhanced the C max, AUC, MRT, t 1/2, and decreased the clearance of metoprolol possibly through the inhibition of CYP enzymes involved in the metabolism of metoprolol.”
Effect of naringenin on the pharmacokinetics of metoprolol succinate in rats
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback