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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Metolazone
supplement:
Potassium
Research Papers that Mention the Interaction
“significantly reduced the renal clearance of metolazone to 33 +/- 7 ml/min and potassium excretion with maximum 30%, while diuretic and saluretic effects were significantly increased with maximum 30%.”
Some effects of metolazone on electrolyte transport.“Urinary excretion of potassium was significantly increased after MET , but was less than that of sodium.”
[Pharmacological study on diuretic action of 2-methyl-3-(o-tolyl)-6-sulfamyl-7-chloro-1, 2, 3, 4-tetrahydro-4-quinazolinone (metolazone) (author's transl)].
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