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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methylselenocysteine
drug:
Interleukin-10
Research Papers that Mention the Interaction
“Serum levels of IL-6, HGF, and IL-10 were significantly decreased at day 3 in mice receiving MSC when compared to control mice (P < 0.05).”
Human Stem Cells Promote Liver Regeneration After Partial Hepatectomy in BALB/C Nude Mice.“We found that MSC exosomes upregulated IL‐10 and TGF‐&bgr;1 from PBMCs, thus promoting proliferation and immune‐suppression capacity of Tregs.”
“For both T and B cells, MSC co-colture induced a statistically significant increase in IL-10 and TGFβ and decrease of GM-CSF and IFNγ, as compared with MV incubation.”
“To note, in a HLA-G-mediated fashion, MSC facilitated the expansion of a CD4low/CD8low T subset that had decreased secretion of IFN-γ, and an induced secretion of the immunomodulatory cytokine IL-10.”
“Moreover, the level of TGF-β was increased by both treatments; however, interleukin-10 was increased only by MSC treatment.”
“ MSC co-transplantation increased CD4 + CD25 + FOXP3 + regulatory T cell numbers, apoptotic CD8-positive T cells, and IL-10 and TGF-beta expression at the implantation site.”
“Hepatocyte growth factor (HGF) and interleukin 10 levels increased with MSC treatment.”
“Analysis of serum samples and colon homogenates showed that local MSC therapy resulted in increased levels of interferon-γ, indoleamine 2,3-dixoygenase, and interleukin-10.”
Endoscopic Administration of Mesenchymal Stromal Cells Reduces Inflammation in Experimental Colitis.“ IL-10 concentration increased in DCs treated with MSC (Vit E) and MSC (Se) CM.”
“On the other hand, the MSC (Vit E) CM and MSC (Se) CM decreased the IL-10 level and increased IL-12, T-bet, and RORγt.”
“Treatment of PBMCs with MSC CM decreased IL-10 level, FOXP3, and RORγt expression.”
Vitamin E and selenium improve mesenchymal stem cell conditioned media immunomodulatory effects.
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