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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methylselenocysteine
drug:
Atorvastatin
Research Papers that Mention the Interaction
“ATV‐MSCs … with ATV administration … enhanced MSC recruitment rate by 3.9%∼24.0%, improved left ventricular ejection fraction (LVEF) by 2.0%∼16.2%, and reduced infarct size in all groups 6 weeks post‐AMI with most prominent improvement in mid groups and still effective in late groups.”
Optimization of Timing and Times for Administration of Atorvastatin‐Pretreated Mesenchymal Stem Cells in a Preclinical Model of Acute Myocardial Infarction“Human MSC treatment with 1 and 10 μM simvastatin or atorvastatin resulted in progressively reduced cell viability, which was associated with a decline in NF-κB p65.”
“Four weeks after AMI, ATV combined with MSC treatment resulted in improved cardiac function and reduced infarct area.”
Atorvastatin treatment improves the effects of mesenchymal stem cell transplantation on acute myocardial infarction: the role of the RhoA/ROCK/ERK pathway.“CONCLUSIONWhen administered in combination with MSCs, atorvastatin increases MSC access and/or survival within the injured brain and enhances functional recovery compared with monotherapy.”
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