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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methylprednisolone
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Combined treatment with atorvastatin calcium and methylprednisolone can improve the outcomes of MS relapse compared with glucocorticosteroid alone.”
Atorvastatin calcium in combination with methylprednisolone for the treatment of multiple sclerosis relapse.“The mechanism is not obvious, but it was suggested that MP may have a direct effect on the integrity of cardiac or smooth muscles, causing alterations in calcium and potassium flux across cell membranes.”
“Mineral and calcium content was slightly increased in the MP group.”
Effect of low-dose methylprednisolone on calcium balance and bone composition in rats“ MP inhibited cellular oxygen consumption, suppressed the inhibitory effect of lanthanum but not that of cycloheximide on oxygen consumption, blocked the [Ca2+]i rise in response to calcium ionophore A 23187, and decreased phospholipid turnover.”
“Both lumen-to-mucosa and mucosa-to-lumen fluxes of calcium were lower in the treated than in the control suckling rats, indicating that the permeability of the mucosal membrane to calcium was decreased with injection of methylprednisolone.”
“Intramuscular injection of methylprednisolone (2.5 mg/100 g body weight daily for 5 days) suppressed absorption of calcium from the jejunum + ileum of the suckling rats only.”
“Some of authors suggest that MP may have a direct effect on the integrity of cardiac muscles, causing alterations in calcium and potassium flux across cell membranes.”
Bradycardia due to Methylprednisolone Therapy.
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