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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Methylergonovine
drug:
Methysergide
Research Papers that Mention the Interaction
“Bredberg et al. showed that methysergide is probably a prodrug for its active metabolite methylergometrine.”
History of Methysergide in Migraine“Our findings may be relevant to the treatment of migraine if methylergometrine contributes to the effect of methysergide.”
“The formation … MEM after MS administration was relatively low and appeared to … saturable since the formation clearance of MEM decreased significantly from 3.5 to 1.9 ml/min per kg for the low and the high rate of iv infusion of MS, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)”
Pharmacokinetics of methysergide and its metabolite methylergometrine in the rat.
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