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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methylene Blue
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“Methylene blue (CAS 61-73-4, MB), a guanylyl cyclase and/or NO synthase inhibitor, was … and nociceptive at 5 and 40 mg/kg doses, respectively, 5 mg/kg dose of MB significantly increased the antinociceptive effect of pyridoxine , but did not change it at 40 mg/kg dose.”
“On the other hand, pyridoxine significantly decreased the antinociceptive effect of MB and reversed the MB-induced nociception to antinociception.”
The role of L-arginine/nitric oxide pathway in the antinociceptive activity of pyridoxine in mouse.“Erythrosine, eosine Y, rose bengal, mercurochrome, methylene blue , azure A and azure B accelerated the photodecomposition of pyridoxine and pyridoxamine at pH 5–9, but fluorescein and acid red did not.”
Effect of dyes on the photodecomposition of pyridoxine and pyridoxamine
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