supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Methylene Blue
supplement:
Ascorbate
Research Papers that Mention the Interaction
“ Methylene blue and ascorbate (Asc), used commonly as the reducing system for IDO activity determination, significantly affected the enzymatic activity of IDO2: In combination, the two reductants increased the apparent Km‐ and kcat‐values 8‐ to 117‐fold and 2‐fold, respectively.”
“ Methylene blue and ascorbate , used commonly as the reducing system for IDO activity determination, significantly affected the enzymatic activity of IDO2: in combination, the two reductants increased the apparent Km - and kcat -values 8-117- and 2-fold, respectively.”
Methylene blue and ascorbate interfere with the accurate determination of the kinetic properties of IDO2“Loading cells with ascorbate also partially prevented oxidation of dihydrofluorescein by methylene blue.”
“ Methylene blue markedly inhibited guanylate cyclase activation by sodium nitrite in the presence of cysteine or ascorbate and similarly inhibited enzyme activation by amyl nitrite either in the absence or presence of cysteine or ascorbate.”
Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback