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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Methyldopa and Yohimbine

supplement:

Yohimbine

Research Papers that Mention the Interaction

The vasoconstrictor effect of 500 ng/ml alpha-methyldopa was fully inhibited in the presence of 10(-7) M yohimbine.
Gynecologic and obstetric investigation  •  1992  |  View Paper
Efaroxan was about tenfold more potent than yohimbine and SK & F86466 at antagonizing the hypotensive effects of α-methyldopa.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  1999  |  View Paper
Yohimbine significantly antagonized the protective action of methyldopa.
Archives internationales de pharmacodynamie et de therapie  •  1993  |  View Paper
Yohimbine antagonized pupillary dilation induced by both clonidine and methyldopa.
Journal of ocular pharmacology  •  1990  |  View Paper
The alpha-adrenoreceptor blocking agent yohimbine increased the nialamide-induced accumulation of normetanephrine and completely antagonized the actions of alpha-methyldopa and FLA 136, indicating that the effects of the two drugs are due to stimulation of alpha-adrenoreceptors.
Naunyn-Schmiedeberg's archives of pharmacology  •  1979  |  View Paper