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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methyldopa
supplement:
Phenethylamines
Research Papers that Mention the Interaction
“ Phenethylamine synthesis was markedly reduced by α-methyldopa , an inhibitor of aromatic l-amino acid decarboxylase.”
Conversion of Phenylalanine to Phenethylamine in Patients with Phenylketonuria“ α-Methyl substituted derivatives of the indoles and phenethylamines increased dramatically psychomotor stimulant effects.”
Structure activity relations of some indolealkylamines in comparison to phenethylamines on motor activity and acquisition of avoidance behavior“Modifications in the phenylethylamine structure led to changes in activity towards biogenic amine uptake and release: (a) the introduction of a beta-OH …-methylation increased the potency towards uptake inhibition and release stimulation, with the exception of 3H-NE release: in fact, the releasing activity of phenylethylamine … alpha-methylation; (….”
“ Methyldopa (α-methyl-3,4-dihydroxyphenyl-alanine), α-methyl- meta -tyrosine and their respective α-methyl-dihydroxyphenethylamines were demonstrated to be capable of antagonizing the cardiovascular actions of phenethylamine and amphetamine, but not norepinephrine, after appropriate pretreatment in dogs.”
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