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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methyldopa
supplement:
Ferric Ion
Research Papers that Mention the Interaction
“The tight binding of ferric iron to methyldopa is predicted to alter the biodistribution characteristics of the complex with respect to the unchelated components.”
The interaction of orally administered iron with levodopa and methyldopa therapy“alpha-Methyl-3, 4-dihydroxyphenylalanine alpha-methylDOPA ) complexed with ferric ion (2:1) showed the greatest superoxide scavenging potency amongst the catecholamine-iron complexes.”
Superoxide radical scavenging and attenuation of hypoxia-reoxygenation injury by neurotransmitter ferric complexes in isolated rat hepatocytes“The ferric form of iron binds strongly to methyldopa , presumably resulting in the decreased methyldopa absorption.”
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