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Discover Supplement-Drug Interactions

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Possible Interaction: Methoxyflurane and Perillyl Alcohol

Research Papers that Mention the Interaction

Allyl alcohol-induced hepatotoxicity was enhanced when allyl alcohol (32 mg/kg) was administered 4 hr before or up to 8 days after a single 10-min exposure to methoxyflurane vapors.
The possibility that methoxyflurane increases alcohol dehydrogenase-dependent oxidation of allyl alcohol to acrolein, the proposed toxic metabolite, was evaluated by measuring the rate of acrolein formation in the presence of allyl alcohol and liver cytosol.
Drug metabolism and disposition: the biological fate of chemicals  •  1989  |  View Paper