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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Methotrexate and Vitamin D

supplement:

Vitamin D

Research Papers that Mention the Interaction

A decrease in 25(OH)D3 levels during MTX therapy was observed in children with ALL that developed severe oral mucositis.
Supportive Care in Cancer  •  2018  |  View Paper
Twins have multiple mutations: a CC mutation …>C in methylenetetrahydrofolate reductase (MTHFR) gene, CC mutations of three SNPs in the adenosine receptor gene ADORA2A (rs3761422_4217241T>C, rs2267076_4221164T>C, rs2236624_4226593T>C), and … genotype in SNPs ATIC_rs2372536_347C>G, MTHFD1_rs2236225_1958G>A. These mutations are known to predict a worse outcome of MTX ….
International journal of immunopathology and pharmacology  •  2016  |  View Paper
Adding vitamin D supplementation to methotrexate may protect lipid homeostasis, specifically cholesterol and triglycerides.
The Journal of dermatological treatment  •  2021  |  View Paper