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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Methotrexate and Vitamin B 12

supplement:

Vitamin B 12

Research Papers that Mention the Interaction

Alteration of folate metabolism and/or vitamin B12 levels through intravenous or intrathecal administration of MTX might exist, although vitamin B12 and other essential nutrients were managed using intravenous hyperalimentation.
Neuropathology : official journal of the Japanese Society of Neuropathology  •  2014  |  View Paper
We suggest that Vit B12 can be used to reduce the toxic effects of MTX.
Journal of molecular histology  •  2021  |  View Paper
Consequently, Vit B12 potentially is a protective agent against damage caused by MTX.
We investigated Vit B12 as a possible protective agent against testicular damage caused by MTX treatment.
Biotechnic & histochemistry : official publication of the Biological Stain Commission  •  2021  |  View Paper