Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Methotrexate and Riboflavin



Research Papers that Mention the Interaction

Riboflavin influences uptake of chemotherapeutic drugs in at least one instance ( methotrexate ) into neoplastic cells.
Cancer research  •  1973  |  View Paper
Riboflavin competitively inhibits the unidirectional influx of methotrexate and possibly utilizes this carrier, at least in part, for its own transport.
Biochemical pharmacology  •  1970  |  View Paper
Riboflavin , a natural ingredient of the growth medium, and folinic acid were found to be able to partially slow down the apparent rate of influx of amethopterin.
Biochimica et biophysica acta  •  1965  |  View Paper