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Discover Supplement-Drug Interactions

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Possible Interaction: Methotrexate and Riboflavin

supplement:

Riboflavin

Research Papers that Mention the Interaction

Riboflavin influences uptake of chemotherapeutic drugs in at least one instance ( methotrexate ) into neoplastic cells.
Cancer research  •  1973  |  View Paper
Riboflavin competitively inhibits the unidirectional influx of methotrexate and possibly utilizes this carrier, at least in part, for its own transport.
Biochemical pharmacology  •  1970  |  View Paper
Riboflavin , a natural ingredient of the growth medium, and folinic acid were found to be able to partially slow down the apparent rate of influx of amethopterin.
Biochimica et biophysica acta  •  1965  |  View Paper