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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methotrexate
supplement:
Riboflavin
Research Papers that Mention the Interaction
“ Riboflavin influences uptake of chemotherapeutic drugs in at least one instance ( methotrexate ) into neoplastic cells.”
Riboflavin and cancer: a review.“ Riboflavin competitively inhibits the unidirectional influx of methotrexate and possibly utilizes this carrier, at least in part, for its own transport.”
Riboflavin-methotrexate interactions. Photochemical reaction and competition for transport in the L1210 mouse leukemia cell.“ Riboflavin , a natural ingredient of the growth medium, and folinic acid were found to be able to partially slow down the apparent rate of influx of amethopterin.”
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