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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Methotrexate and Quercetin



Research Papers that Mention the Interaction

A significant reduction in the levels of knee-joint inflammatory mediators were observed with combined quercetin and methotrexate treatment.
Inflammopharmacology  •  2018  |  View Paper
The results also showed that the concurrent administration of quercetin and methotrexate did not offer greater protection than the administration of a single agent.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2017  |  View Paper
Conclusions: In conclusion, renal toxic effects of MTX may be alleviated by QE.
However, QE significantly suppressed MDA level, compensated deficits in the anti-oxidant defenses [reduced SOD, GSH-Px, and CAT levels] in kidney tissue resulted from MTX administration.
Renal failure  •  2015  |  View Paper
Because increased GGH expressions were repeatedly associated with resistance to methotrexate , concomitant intake with quercetin should be monitored carefully.
The Journal of nutritional biochemistry  •  2015  |  View Paper
Pre-treatment of mice by gavage …/day for 10 days) and QE (50mg/kgbw/day for 10 days) caused a significant decrease in CAs and … aberrant cells with CAs induced by intramuscular treatment of the mice with MTX (10mg/kgbw/day for 3 days), … group treated with MTX alone.
Mutation research  •  2012  |  View Paper
QT co-administered with MX reversed this hepatotoxicity (p<0.05).
Inflammation  •  2021  |  View Paper