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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Methotrexate and Progesterone



Research Papers that Mention the Interaction

MTX given dose dependently to rats for 20 days prevented vaginal cyclicity and caused a reduction in serum progesterone and estradiol.
Cell biochemistry and function  •  2011  |  View Paper
MTX combined with hCG 10 U/mouse or progesterone 0.2 mg/mouse was shown to have antagonistic effect to terminate early pregnancy.
Treatment with MTX caused a decrease of serum progesterone level on day 13 of pregnancy.
Yao xue xue bao = Acta pharmaceutica Sinica  •  1998  |  View Paper
In combination of progesterone and anticancer drugs, the antitumor effect of methotrexate or vincristine was markedly enhanced by progesterone in YS bearing rats.
Gan to kagaku ryoho. Cancer & chemotherapy  •  1989  |  View Paper