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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methotrexate
supplement:
Niacin
Research Papers that Mention the Interaction
“ NIC significantly solublized MTX by forming hydrogen bonds with MTX.”
Co-delivery of methotrexate and nicotinamide by cerosomes for topical psoriasis treatment with enhanced efficacy.“ Nicotinamide decreased the methotrexate‐induced hepatotoxicity.”
“The combination of nicotinamide and thalidomide or methotrexate provided a powerful synergistic inhibition of murine collagen‐induced arthritis.”
“If methotrexate is administered in conjunction with either nicotinamide or methionine, the rise in the death rate and in GOT and GPT activities associated with methotrexate application is markedly reduced.”
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