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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methotrexate
supplement:
Genistein
Research Papers that Mention the Interaction
“Our in vitro studies showed that genistein in certain concentrations protected cultured SECs from MTX cytotoxic effects.”
Flavonoid genistein protects bone marrow sinusoidal blood vessels from damage by methotrexate therapy in rats“In addition, genistein (a tyrosine phosphorylation inhibitor) significantly enhanced the resistance of L1210/0 cells to MTX.”
“After 5 h of treatment with 50 microM genistein, methotrexate uptake was decreased by nearly 50% and the cells were protected from methotrexate cytotoxicity.”
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