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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Methotrexate and Docosahexaenoic Acid

Research Papers that Mention the Interaction

The DHA- and MTX-containing phosphatidylcholine was more effective than that containing stearic acid, and DHA appeared to synergize with MTX when they were added as free agents or covalently linked in the phospholipid.
Anti-cancer drugs  •  2002  |  View Paper
The permeability of FITC-dextran increased remarkably in the MTX-treated mice and oral administration of docosahexaenoic acid ethyl ester (DHA) protected the small intestine from the increase in the small intestinal permeability induced by the MTX treatment.
The MTX treatment decreased retinol concentration in plasma of mice and the coadministration of DHA maintained its concentration to the level of control mice.
Life sciences  •  1998  |  View Paper