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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Methotrexate and Coenzyme Q10

supplement:

Coenzyme Q10

Research Papers that Mention the Interaction

Based on our results we postulated that CoQ10 up regulates autophagy pathway that could explain its protective properties against lung and liver fibrosis caused by methotrexate treatment in current study rat model.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2019  |  View Paper
CoQ10 administration potentiated the antiarthritic effect of MTX.
These results revealed that CoQ10 can serve as a useful adjuvant and promote the safe use of MTX in the management of arthritis, not only by potentiating the antiarthritic effect of MTX, but also by alleviating MTX-induced hepatocellular injury.
International immunopharmacology  •  2015  |  View Paper