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Discover Supplement-Drug Interactions
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Last Updated: 3 months ago
drug:
Methotrexate
supplement:
Annona Muricata Whole
Research Papers that Mention the Interaction
“ MTX slightly suppressed paw inflammation and hyperalgesia at the highest dose (1 mg/kg).”
FK506 is superior to methotrexate in therapeutic effects on advanced stage of rat adjuvant-induced arthritis“ Methotrexate pretreatment significantly reduced not only the peripheral leucocyte count but also venom PLA2-induced paw oedema.”
“Orally dosing AA rats from days 3 to 17 …, CS-A (3 and 5 mg/kg) or MTX (0.5 and 1 mg/kg), significantly (… or equal to 0.01) reduced paw inflammation (100% reduction), increased final body wt 40-50 … controls and decreased LAF activity from splenic leukocytes.”
“When these immunized rats were treated orally with low doses of methotrexate (150-600 micrograms/kg/week) a statistically significant suppression of paw inflammation was observed.”
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