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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Methotrexate and Annona Muricata Whole

Research Papers that Mention the Interaction

MTX slightly suppressed paw inflammation and hyperalgesia at the highest dose (1 mg/kg).
Inflammation Research  •  2001  |  View Paper
Methotrexate pretreatment significantly reduced not only the peripheral leucocyte count but also venom PLA2-induced paw oedema.
The Journal of pharmacy and pharmacology  •  1992  |  View Paper
Orally dosing AA rats from days 3 to 17 …, CS-A (3 and 5 mg/kg) or MTX (0.5 and 1 mg/kg), significantly (… or equal to 0.01) reduced paw inflammation (100% reduction), increased final body wt 40-50 … controls and decreased LAF activity from splenic leukocytes.
International journal of immunopharmacology  •  1988  |  View Paper
When these immunized rats were treated orally with low doses of methotrexate (150-600 micrograms/kg/week) a statistically significant suppression of paw inflammation was observed.
The Journal of rheumatology  •  1985  |  View Paper