Possible Interaction: Methionine and Zinc Sulfate

“The stimulatory effects of zinc sulfate on Runx2, OPG, or regucalcin mRNAs were significantly prevented in the presence of cycloheximide ( 10−7 M ), an inhibitor of protein synthesis, or 5,6-dichloro-1-β-d-ribofuranosyl-benzimidazole (10−6 M), an inhibitor of transcription activity.”

“Protein synthesis in the diaphyseal and metaphyseal tissues obtained from 7- or 14-day-old rats was significantly decreased by the addition of dipicolinate 10−3 M ), a chelator of zinc ion, into the reaction mixture, while it was significantly enhanced by zinc sulfate (10−4 M).”

“Abstract Zinc sulphate in the range of 10−4 to 2× 10−5 M prevents the binding of C 1 to antigen antibody complexes, and the initation of the cascade of events in the classical complement pathway leading to cell lysis.”

“In case of E. coli biofilms, the inhibition was more pronounced: zinc sulfate in a concentration of 0.005 M reduced its growth by 4.6 times in comparison with the positive control.”