Possible Interaction: Methionine and Valine

“Furthermore, the chlamydial growth inhibition induced by leucine, isoleucine, methionine , or phenylalanine was completely reversed by concomitant addition of valine.”

“ Serum methionine fell significantly in both groups as did valine and isoleucine in the controls.”

“There was a linear increase in concentrations of tyrosine, valine , glycine and serine as dietary DLM supplementation level increased.”

“ Valine uptake was inhibited by leucine and alpha-aminoisobutyric acid and by high concentrations of L-alanine, L-lysine, cycloleucine, L-glutamine, and L-methionine , but not by 2-(methyl-amino)-isobutyric acid.”

“ L-methionine inhibits L-valine uptake and a 2.5 mM concentration abolishes the capacity of enterocytes to accumulate the substrate.”

“l -Ethionine and l -norleucine, as well as a number of neutral, nonpolar amino acids (leucine, isoleucine, valine , and alanine) also inhibit methionine uptake.”

“Excess methionine added to a diet limiting in valine inhibit...”

“Of a number of sugars and amino acids tested, isoleucine, methionine , and leucine were the most potent inhibitors of valine uptake into lipid.”

“In contrast, the Na+-insensitive uptake of methionine is concentrative and subject to inhibition by such amino acids as phenylalanine, leucine, and valine , although not in a manner to indicate that the uptake is mediated by a single agency.”

“Eventually, a combined asm10 overexpression and supplementation of L-methionine and L-valine resulted in a 5-fold increase of AP-3, from 42 ± 2 mg L-1 to 246 ± 6 mg L-1 , without any noticeable accumulation of PND-3.”