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“This effect was drastically enhanced (ED50 = 0.06 microM) by the aminopeptidases M and B inhibitor bestatin (10 microM), which elicited a 40-fold increase in NN potency.”
The Journal of pharmacology and experimental therapeutics • 1995 | View Paper
“The formation of [ 3 H]Tyr, presumably occurring under the action of membrane-bound aminopeptidases, is reduced in the presence of either 10 −4 M puromycin or 2.10 −5 M bestatin by about 40% and 75%, respectively.”