Possible Interaction: Methionine and Tyramine

“In higher concentrations (up to 3 10−3 M) tyramine causes an increase in force of contraction which is characterized by a slowing of relaxation of the isometric contraction curve.”

“Many substances, but not amino acids, H, M , and N receptor agonists, can inhibit the uptake of tyramine.”

“3 Cocaine (1 × 10−5 M ) reduced the increased outflow of NA induced by tyramine at rest and during field stimulation, without modifying DOPEG‐outflow.”

“Reserpine pretreatment, 10 −4 M cocaine, and gangliectomy reduced the contraction caused by tyramine without changing maximal responses.”

“ Tyramine (10−3 M) in the presence of a monoamine oxidase inhibitor (pheniprazine, 10−3 M ) and a phosphodiesterase inhibitor (theophylline, 10−3 M) significantly (P < 0.01) stimulated renin release when values were compared to control observations for media containing only the inhibitors.”