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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
Research Papers that Mention the Interaction
“Moreover, the estimated net release of t-PA was enhanced during methionine loading (two-way ANOVA; P=0.02), but this was unaffected by vitamin C supplementation.”
Effects of acute methionine loading and vitamin C on endogenous fibrinolysis, endothelium-dependent vasomotion and platelet aggregation.“In leukemic mice, administration of L-methionine significantly increased homocysteine levels (49.0 μmol/mL and < 6.0 μmol/mL in the treated and nontreated groups, respectively) and reduced tPA levels to baseline concentrations.”
Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.“ TPA also synergistically promoted DNA synthesis in combination with purified growth factors including fibroblast growth factor, insulin ( 10−6‐10−5 M ), and epidermal growth factor.”
“Our study demonstrates that those with the Met S have significantly higher levels of PAI-1 and t-PA antigen , factors known to increase the risk of cardiovascular disease.”
The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels“Sphingomyelin vesicles (2 x 10-6 M ) enhanced TPA (5 x 10-10 M)-induced adherence 2-fold from 12 to 24% of the total population.”
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