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Last Updated: 2 months ago

Possible Interaction: Methionine and Threonine

supplement:

Methionine

supplement:

Threonine

Research Papers that Mention the Interaction

It is found by computer simulated molecular model that the replacement of Thr by Met which has a larger and longer side chain might cause steric hindrance, and change the number of H-bonds.
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi  •  2003  |  View Paper
We suggest that loss of hydrophobicity during conversion of methionine to threonine is responsible for the more severe presentation of the first family, whereas maintenance of the hydrophobic nature of the amino acid with conversion to valine resulted in a less severe variant of epidermolysis bullosa simplex.
The Journal of investigative dermatology  •  2001  |  View Paper
Fasting Met concentration (15 +/- 4 mumol/liter) and the … depressed after 9 days of L & U. Supplementation with Met caused an expected increase of Met concentration (25 +/- 6 ….039 +/- 0.007) and a profound decrease of Thr concentration (119 +/- 28 to 77 +/- 22 ….027 to 0.124 +/- 0.028).
These studies confirm Met as the first-limiting amino acid in lupin protein and suggest that Thr becomes limiting when Met is provided in adequate amounts.
The Journal of nutrition  •  1983  |  View Paper
3) Threonine and methionine are interrelated to each other and form a loop structure.
Amino Acids  •  2006  |  View Paper
The substitution of methionine with glycine, threonine , or alanine caused a complete loss of the neotropic activity of the peptide.
Izvestiia Akademii nauk. Seriia biologicheskaia  •  2005  |  View Paper
Increasing doses of Thr resulted in increased (P < 0.05) concentrations of methionine , isoleucine, histidine and lysine in whole-body protein.
The British journal of nutrition  •  1997  |  View Paper
Threonine was most effective in increasing the degree of parasitaemia but its effect was further enhanced when it was combined with dietary excess of certain other amino acids, notably valine, isoleucine and methionine.
Transactions of the Royal Society of Tropical Medicine and Hygiene  •  1984  |  View Paper
The addition of threonine to the methionine supplemental pea protein concentrate significantly reduced the free isoleucine and leucine in the plasma.
Poultry science  •  1982  |  View Paper
In rats fed a high tyrosine diet supplemented with methionine plus threonine , liver p-hydroxyphenylpyruvate hydroxylase activity was not higher than that of the 10% casein group, but liver homogentisate oxidase activity increased significantly.
When excess tyrosine was included in the 10% casein diet, free tyrosine concentrations in plasma, liver, muscle and brain were extremely elevated, but when the high tyrosine diet was supplemented with extra casein or methionine plus threonine , their plasma and tissues tyrosine concentrations lowered significantly.
Journal of nutritional science and vitaminology  •  1976  |  View Paper
Most amino acid concentrations declined gradually during the first four weeks of life, but methionine plus one half cystine, phenylalaine, threonine and serine concentrations decreased sharply between two and four weeks.
Poultry science  •  1976  |  View Paper
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