Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“Using increasing concentrations of sulphanilamide , these authors showed that it inhibits sequentially the synthesis of methionine and xanthine by the organism.”
“Vitamin B12 has been reported (Shive, 1950) to potentiate PABA action as, in its presence, higher concentrations of SA are required to inhibit the biosynthesis of methionine , xanthine and serine.”
“Strains that became resistant to 2-Cl-PABA were shown, however, not to be resistant to SAN, and from these data Strandskov concluded that SAN inhibits a step in methionine synthesis in addition to that inhibited by 2-Cl-PABA.”