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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Substance P
Research Papers that Mention the Interaction
“ Substance P caused dose-dependent increases in plasma tissue plasminogen activator (t-PA) antigen (from 3.0+/-0.….2 to 4.2+/-0.4 i.u./ml; P<0.001), which were augmented during acute methionine loading (4.7+/-0.4 to 5.….u./ml respectively; P</=0.05).”
Effects of acute methionine loading and vitamin C on endogenous fibrinolysis, endothelium-dependent vasomotion and platelet aggregation.“CGRP and SP enhanced the leishmanicidal capacity of macrophages at 10−7M, and 10−5 M , respectively, whereas SOM was without effect.”
“ Substance P provoked a dose-dependent decrease of contraction frequency; this effect was diminished by atropine ( 10−5 M).”
The effect of compound 48/80, substance P and pentagastrin on the isolated guinea pig atrium“Bombesin, substance P , and cholecystokinin-octapeptide each elicited concentration-dependent isometric contractions that were reduced by 10−8 M or 10−7 M vasoactive intestinal peptide (P<0.01).”
“Tetrodotoxin (TTX, 10−7 M ) decreased the maximum SP response to 11% of the control value.”
“Perfusion with SPME at a concentration of more than 10-6 M produced an increase in the amplitudes of the compound action potential and negative summating potential in a dose-dependent manner.”
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