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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Sorafenib
Research Papers that Mention the Interaction
“Conclusions: Tumor MET levels were higher in patients treated with sorafenib.”
Tumor and circulating biomarkers in patients with second-line hepatocellular carcinoma from the randomized phase II study with tivantinib“We investigated the potential association between MET expression and therapeutic response to sorafenib in patients with HCC.”
“ MET overexpression was shown as a negative prognostic factor in HCC after sorafenib failure.”
“Furthermore, we found that Sorafenib induced c‐Met phosphorylation at Tyr‐1349 but not Tyr‐1234, which is probably mediated by inhibition of receptor tyrosine phosphatase density enhanced phosphatase‐1 (DEP‐1).”
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